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Primary outcome The primary outcome, major adverse cardiovascular events (MACE), was reported in all 11 included studies, comprising of 91,490 participants with 4386 MACE events in the intervention group and 4884 MACE events in the placebo group
Low and elevated dose adjustments
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Instead, the researchers were hit with nondelivery scams, in which the sellers requested additional, hefty payments, supposedly needed to get through customs
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But a creatinine increase exceeding 30% from baseline, or one that continues rising beyond the first 12-16 weeks, needs investigation
