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Dihexa crosses the blood-brain barrier and activates the hepatocyte growth factor (HGF) / c-Met receptor pathway, which governs neuron survival and synapse formation
"Immunohistochemical distribution of delta sleep inducing peptide in the rabbit brain and hypophysis"
1989 Feb 27;481(1):165-8
This does not mean subcutaneous is ineffective, but it means you cannot simply transpose a nanomole-per-kilogram IV number to a subcutaneous protocol and expect equivalent CNS exposure
10.1111/ene.14108 9 BjrklundG.PeanaM.MaesM.DadarM.SeverinB
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