Mechanism of action: 1) Activation of amylin receptors (AMY1, AMY2, AMY3 heterodimers of calcitonin receptor with RAMP1/2/3) in area postrema and NTS appetite suppression and enhanced satiation
Erlotinib was first approved by the Food and Drug Administration on November 18, 2004, as a monotherapy for patients with locally advanced or metastatic non-small cell lung cancer (NSCLC)
New England Journal of Medicine , 390(8), 701-714
Reconstitution Supplies Needed AOD-9604 lyophilized powder (typically 2 mg or 5 mg vials) Bacteriostatic water (sterile water with 0.9% benzyl alcohol preservative) Insulin syringes (typically 0.3 mL or 0.5 mL with 29-31 gauge needles) Alcohol prep pads Sharps disposal container Step-by-Step Reconstitution Protocol Step 1: Prepare Your Workspace Wash hands thoroughly with soap and water
Solutions mixed with sterile water must be used within 24-72 hours
10.1038/s41467-021-26066-5 138 PhamM