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A limitation with the use of GLUTag cells, as well as other models for epithelial cells, is that the cells have lost their polarization, which may affect the amino acid sensing mechanisms, as different amino acid transporters are situated on the apical compared to the basolateral membrane [28]

In contrast, the injectable form is directly introduced under the skin, bypassing the digestive tract altogether

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A key metabolic catalyst that shuttles long-chain fatty acids into mitochondrial centers to be converted into usable cellular energy

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