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Kinetic parameters Steady-state kinetics constants were estimated with purified laccase variants for ABTS (Panreac, A1088), DMP (Merck, D135550), guaiacol (Thermo Scientific, 120192500) and sinapic acid (Apollo Scientific, BIS8112) in 100 mM sodium phosphatecitrate buffer pH 5.0 or 6.0
It plays a crucial role in maintaining cellular health and also combats oxidative stress
The biomarker changes were shown to correspond with endpoints such as improved gait and body composition
This may be useful for conditions such as Parkinson's disease
doi:10.1021/cr500131f
[2] The Phase 3a REDEFINE 2 trial then tested once-weekly CagriSema (cagrilintide 2.4 mg plus semaglutide 2.4 mg) against placebo in 1,206 adults with obesity and type 2 diabetes over 68 weeks, reporting a mean bodyweight change of 13.7% versus 3.4% for placebo
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