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Third, the discovery that MOTS-c also plays roles in immune regulation, particularly in suppressing innate immune overactivation, has opened research directions in inflammation-driven aging, autoimmunity, and potentially long-term sequelae of infections

These individuals can receive an injectable form of the vitamin, which altogether bypasses the gastrointestinal tract

doi: 10.4049/jimmunol.167.8.4686 55 TamamuraHFujisawaMHiramatsuKMizumotoMNakashimaHYamamotoNet al

According to the NIH Office of Dietary Supplements, absorption issuesnot intake aloneare a leading cause of low B12 levels

doi: 10.1124/mol.117.110841 160 ZayedNAfifHChabaneNMfuna-EndamLBenderdourMMartel-PelletierJet al

As with all other vitamins and supplements, never give your dog vitamin B12 without first discussing it with your veterinarian