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Over recent years two trials with nerve growth factor (NGF) designed to protect forebrain cholinergic neurons (early to moderate stage AD patients) were terminated after phase I [15,16] (NCT00017940, NCT00876863)

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Over a 28-day period, lean WT mice treated with either compound exhibited increased body weight, replicating results seen in the shorter 14-day study

Always follow the specific reconstitution instructions provided by the compounder when available

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It also increases subjective perception of discomfort