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However, GIP(3-30)NH 2 did not affect insulin secretion in the fasting state ( In gastric bypass-operated individuals with obesity and no history of diabetes, GIP(3-30)NH 2 does not affect insulin secretion nor plasma glucose levels ( 2 in non-operated individuals, and points to a less important role of GIP in glucose metabolism after gastric bypass surgery ( 2 still appears to differ depending on the type of gastric surgery

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Further changes involving receptor affinity and activation occurred specifically in monotremes