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Among the known methyltransferases, proteins from the NOL1/NOP2/SUN domain (NSUN) family (NSUN1-7) and members of the DNA methyltransferase (DNMT) family are involved, with NSUN2 and NSUN6 being the primary methyltransferases for mRNA m 5 C modification [39]
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Other reasons include: bariatric surgery or bowel resection, age, those with GI diseases such as Crohns and Celiac, people taking Metformin to control their blood sugar and thos taking proton pump inhibitors (Prevacid, Prilosec, etc) for chronic heartburn
Springer Nature Switzerland, Cham, pp 345357 Guo D, Liu Z, Zhou J et al (2024) Significance of programmed cell death pathways in neurodegenerative diseases
Its precisely why GLP-1 medications are being extensively studied for use cases beyond weight loss and diabetes management
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