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The development of inhibitors targeting key enzymes involved in glycolysis and related mechanisms of action are summarized in Table 1
In fact, it has been suggested as a s potential treatment for conditions such as COVID-19, as it improves vascular integrity, and immune response and reduces proinflammatory profiles, which reduces critical levels of disease
74,75 WD40 repeat-containing protein 6 (WDR6) is up-regulated in liver with IR
Asmar, M
Cutaneous melanoma at an advanced stage is resistant to standard cancer treatment (225)
Either Trx and TrxRD are expressed as isoforms for both predominantly cytosolic (Trx1 and TrxRD1) or mitochondrial (Trx2 and TrxRD2) localization (Orrenius et al., 2007)
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