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Chronic ketamine exposure in rodent models (50 mg/kg daily for 8 weeks) leads to significant activation of microglial cells and elevated expression of proinflammatory cytokines, such as IL-6 and IL-1, which correlate with hippocampal neuronal damage (Yin et al., 2022)
The PCRs were performed in triplicate with at least three independent experiments
References Kwon Y, et al
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S100A8 contributes to drug resistance by promoting autophagy in leukemia cells
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