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This review highlights recent developments in enzyme-responsive biomaterials, focusing mainly on polymeric hydrogels, as well as nanoparticles and scaffold-based approaches for delivering enzyme-triggered solutions to various pathologies (Table 1)

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NSAIDs, such as aspirin, inhibit cyclooxygenase (COX) activity, reducing prostaglandin synthesis, directly suppressing neutrophil function, and effectively controlling acute inflammation, although concerns about their safety persist (227)

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Post incubation, the liberated IGF-1 was co-immunoaffinity extracted with the internal reference, using protein A/G MSIA pipette tips (from Thermo Fisher Scientific) loaded with antihuman IGF-1 antibody

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