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A parallel line of work by Chang and colleagues (J Appl Physiol, 2011) examined cultured rat Achilles tendon fibroblasts and reported increased outgrowth, survival and migration alongside elevated phosphorylation of focal adhesion kinase (FAK) and paxillin, the adaptor pair coupling integrin engagement to cytoskeletal reorganisation

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Instead, KPV enters cells through the PepT1 di/tripeptide transporter, which is normally expressed in the small intestine and induced in the colon during IBD

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