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Ristoff E, Hebert C, Njalsson R, Norgren S, Rooyackers O, Larsson A: Glutathione synthetase deficiency: is gamma-glutamylcysteine accumulation a way to cope with oxidative stress in cells with insufficient levels of glutathione
In PBMC ( Figures 4A, B ), intracellular carnitine was the predominant fraction (55.1% in CON and 66.1% in CAR), followed in CON by TML (31.1%) and then by BB (13.8%), whereas in CAR it was followed by BB (18.0%) and then by TML (15.8%)
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This BCAC increases the activation of cytoplasmic phospholipase A2 (cPLA2) by binding to integrin 21 in platelets and promoting platelet hyperresponsiveness, thus promoting thrombosis [239]
It boosts the activity of fibroblasts, the cells that produce collagen and repair ligaments and tendons