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This observation indicates that a single copy of HIF1a sufficiently supports adult neurogenesis and that HIF1a hemizygosity does not influence the efficacy to generate hippocampal adult-born neurons under normal circumstances

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Although semaglutide is not primarily renally excreted, dehydration secondary to gastrointestinal adverse effects may precipitate renal compromise

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Individual response varies, and not everyone achieves the same degree of weight reduction