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Secondary pulses happen during fasting states and after intense exercise [1]
Because the semaglutide injection mimics this fullness response, patients can feel full sooner and stay satisfied for longer, even when eating less food
45 GanF.WangR.LyuP.LiY.FuR.DuY.et al (2021)
73 Avoid potential triggers like high-fat foods, excessive sugar, caffeine, alcohol, or sugar alcohols (sorbitol, xylitol)
313 Similar observations were obtained from healthy humans during euglycemia and T2D patients during meal-tolerance studies
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If you already have asymptomatic gallstones and are starting GLP-1 therapy This is one of the highest-risk situations and one of the most under-discussed
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