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The two peaks could represent exosomes and microvesicles populations, respectively, but the mechanism of secretion was not determined 17

Signaling and Synthesis: The prolonged, unbound presence of IGF-1 LR3 in the bloodstream maximizes the anabolic signaling effect on muscle tissue, activating intracellular signaling pathways that promote protein synthesis and muscle fiber hypertrophy (increase in cell size)

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Genetic and biochemical analysis of glutathione-S-transferase in the oxygen defense system of Drosophila melanogaster