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Abstract Ferroptosis, an iron-dependent, lipid peroxidation-driven programmed cell death, holds substantial promise for cancer therapy, yet its translational potential is hindered by widespread intrinsic resistance

In the serum, Fe 2+ is oxidized by ceruloplasmin to Fe 3+ and then binds with transferrin (TF) to form a TFFe 3+ complex, which is endocytosed through the cell membrane transferrin receptor 1 (TFR1) (Frazer and Anderson, 2014)

T1AM/TAAR1 system reduces inflammatory response and beta-amyloid toxicity in human microglial HMC3 cell line

Studies have shown that people with obesity are often less sensitive to the hormones that make us feel full

Oral iron supplementation should be continued until the reason for supplementation, such as normalizing the hemoglobin level, has been addressed

GLP-1 receptor agonists have transformed the treatment of obesity and Type 2 diabetes, but this breakthrough is the result of decades of scientific innovation and collaboration