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The findings of this study reinforce the growing view that gastrointestinal modulation should not be ancillary to T21 care but should instead be considered a primary target for therapeutic intervention 23,72

Femena et al., 2018)

Fat metabolism

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Several studies have suggested that KD modulates digestive, hormonal, and immune homeostasis via the gut microbiome 197

For instance, semaglutide has been approved and is being researched for indications including obesity, T2DM, reducing cardiovascular risk, chronic kidney disease, NAFLD, and AD, indicating that the development of new indications could provide new growth opportunities for GLP-1 drugs