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a lower absolute value of an NNT indicates a higher degree of effectiveness of a GLP-1RA versus insulin

While SGLT2 inhibitors often result in a weight loss of approximately 23 kg, no reduction in muscle mass or bone mineral density was observed with empagliflozin administration in the EMPA-ELDERLY study [9], which evaluated the effects of empagliflozin on glucose levels and muscle mass in Japanese patients with type 2 diabetes aged 65 years or older with a body mass index (BMI) of 22 kg/m or higher

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