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Cys is conjugated at the N-terminal of peptide sequence
where it caps surface glycans
C22H20D6N2O4S
82 / MUC4 (UniProt ID A0A0G2JMX1) synthetic peptide fragment (Thr1179-Asp1194
β-D-GalNAc with 6-aminohexyl linker/spacer
PE135000: α-GalNAc-PEG3-Thiol label-new Cys is conjugated at theC14H27NO8S 369. 43 An D N acetylgalactosamine (GalNAc) ligand equipped with a free thiol through a hydrophilic PEG3 spacer. The thiol reacts with maleimides to form stable thioether conjugates or with other thiols to form disulfide bonds; it is also compatible with thiol gold chemistry for surface immobilization. This compound enables the construction of hepatocyte targeted therapeutics and research tools that exploit the asialoglycoprotein receptor
