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It follows a diurnal rhythm, with levels typically peaking in the early morning hours and declining throughout the day to reach their lowest point around midnight

However, supplementation should be approached with caution and must strictly follow a doctor's recommendations

J Int Soc Sports Nutr 4:17 Jger R, Purpura M, Shao A et al (2011) Analysis of the efficacy, safety, and regulatory status of novel forms of creatine

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Laboratory personnel