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To date, at least 39 mutations were identified in GLUD1- associated HI

Acknowledgements R.A.K

Multiple well-designed clinical trials have demonstrated SFNs biological activity and therapeutic potential, while also revealing important considerations for its clinical implementation ( Figure 3 )

Its primary job is to neutralize free radicals , which are unstable molecules that can cause oxidative stress

Nature 335 , 632635 (1988)

Other typical agents with reported inhibitory activities on TYR include kojic acid (111,112), methyl gentisate (113,114), ganodermanondiol (71,115), 10-hydroxy-2-decenoic acid (116), Stichopus japonicus extracts (69) and bis (4-hydroxybenzyl)sulphide (117)