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doi:10.1111/jop.70094

MT2 also crosses the blood-brain barrier, producing centrally mediated effects (appetite suppression, libido modulation) that MT1 does not

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A most striking difference from the mammalian glutathione S-transferases, which share a conserved catalytic tyrosine residue, is the lack of this tyrosine in the active site of the plant glutathione S-transferase