Last reviewed: July 18, 2026 Last updated: July 18, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
medical screening is recommended before initiating therapy
The following symptoms, anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia (psychomotor restlessness), hypomania, and mania, have been reported in adult and pediatric patients being treated with antidepressants for major depressive disorder as well as for other indications, both psychiatric and nonpsychiatric
Bkdal TA, Breitschaft A, Navarria A, Hansen CW
Attend all scheduled appointments for dose adjustments, side effect assessment, and metabolic monitoring
Retatrutide is generally given via a weekly injection (just like most other GLP-1)