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Krimpenfort P, Berns A
PHGDH activation fuels glioblastoma progression and radioresistance via Serine synthesis pathway
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In an orthotopic glioblastoma mouse model, PTX-CDs accumulated within intracranial tumours and exerted antitumour effects through ROS-mediated oxidative stress [ At the cellular level, PTX-CDs localised to mitochondria, disrupted mitochondrial membrane potential, and induced oxidative stress-mediated cytotoxicity [ et al
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