The higher dose of Wegovy likely plays a role, as it leads to greater systemic exposure and faster weight loss, which might affect blood flow to the optic nerve
188 GLP-1 Production and Secretion GLP-1, which is a 30aa-long incretin hormone, is secreted by enteroendocrine L-cells present in the distal ileum and colon of the GIT in response to postprandial food intake
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in 2016 demonstrated poor efficacy at 37.5% versus 18.7% placebo response
The active ingredient, bismuth subsalicylate, works by coating the stomach lining, reducing inflammation, and killing bacteria that can cause diarrhea