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A: Hexarelin is considered more potent at equivalent doses in most preclinical research models, producing higher peak GH levels

It acts as an agonist of the growth hormone secretagogue receptor (GHS-R1a), the receptor for the endogenous peptide ghrelin

Jun 2025;48(6):1929-1938

Activates longevity genes like FOXO3, linked to extended lifespan

It is available only by prescription, and outside that approved indication it is prescribed off-label and often dispensed as a compounded preparation through 503A/503B compounding pharmacies for bodybuilding, fat-loss, or anti-aging purposes, uses the FDA has not evaluated or approved

The formulation process introduces variables that affect how much active peptide actually reaches the dermal target tissue