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Severe ASD has been linked to elevated levels of IL-1 and IL-4 in the neonatal blood (Theoharides et al., 2016), and increased serum levels of IL-1 and IL-6 compared to control groups ( Recent data support findings that immune cells activity in ASD subjects is compromised, with amplified inflammatory signaling and reactivity of immune cells such as B-cells, neutrophils and monocytes (Majerczyk et al., 2022)

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Ionizing radiation also causes oxidative stress in tissues, leading to testicular damage

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Integrin beta 1 (ITG1), a critical cell surface protein, is actively expressed in the presence of GHK and thus may serve as a primary target for its anti-fibrotic effect [14]