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Peptides may serve as adjuncts to surgical treatment or may be investigated for cases where surgery is not feasible or has failed
Jiang et al found elevated and sustained p21 expression in aged (24 months old) mice after wounding which when downregulated with p21 siRNA improved aged wound healing rates [27]
N.BanoR.DavidJ
In aged or photodamaged skin, GHK-Cu treatment (1-5 M) suppresses elevated MMP-1 (collagenase-1) expression by approximately 40-60%, as documented through quantitative PCR and Western blot analyses
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