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In contrast to the phosphorylation of ACC2 by AMPK during energy-deficient states, hydroxylation of ACC2 increases under conditions of high glucose content, in particular in skeletal muscle

Endogenous BACE1 was detected with anti-BACE1 antibody

[397] found a significantly increased accumulation of dysfunctional mitochondria in the fibroblasts isolated from SLOS patients under steady-state conditions compared to control cells

Among those with preexisting substance use disorders, GLP-1 takers had lower risks of hospitalization, overdose and suicidal ideation