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The breadth of reported activity reflects the compound's broad gene-expression effects

PMID 9849822)Tier 1 primary [2]Gobburu et al

The BBB is present as a highly selective semi-permeable interface between blood and brain, possessing a defensive network of blood vessels and brain tissues that are complex, dynamic, and prevent the entry of harmful substances such as neurotoxic debris derived from blood, cells, and other microbial pathogens [6]

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Tiliaceae and Mimosaceae were reported by kaali et al