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Nrf2 serves also as a common regulator in modulating autophagy, pyroptosis and ferroptosis

10.1042/BJ20100409 Biochem J

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cDNA microarray analysis of rat Achilles tendon fibroblasts identified the growth hormone receptor as one of the most abundantly up-regulated genes following exposure to the peptide, with concentration- and time-dependent increases confirmed at both mRNA and protein level, and downstream Janus kinase 2 activation observed on subsequent growth hormone stimulation [3]