Some of the most common causes of impaired B12 absorption are: Pernicious anemia more on this shortly Parasitic infections like fish tapeworm and Giardia lamblia Small Intestine Bacterial Overgrowth (SIBO) Familial factors Hypochlorhydria (low stomach acid) Aging stomach acid production declines with age Gastrointestinal surgery that removes significant sections of the terminal ileum Digestive disorders like Crohns disease or celiac disease Certain medications like oral contraceptives, Metformin, proton pump inhibitors (PPIs) and others (5) If a person is consuming a reasonable about of B12-rich foods in the diet but B12 levels are still low, this may indicate an issue with B12 absorption
What Is Vitamin B12 Exactly
Currently only on Reta only
However, there is no evidence that normal dietary fibre intake causes clinically significant B12 malabsorption
Drug interactions Diclofenac: Diclofenac like other NSAIDs should not be administered concomitantly with: - Aspirin: because it alters the bioavailability of both drugs
Certain health conditions such as intestinal or stomach problems, poor nutrition, cancer, HIV, pregnancy, old age, veganism, and alcoholism can cause vitamin B12 deficiency