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In contrast, sustained or recurrent heat stress may induce Sertoli cell dysfunction and dedifferentiation, disrupt the bloodtestis barrier, and ultimately lead to persistent spermatogenic impairment or, in severe cases, irreversible infertility (Hu et al., 2021

Daunorubicin activates NFkappaB and induces kappaB-dependent gene expression in HL-60 promyelocytic and Jurkat T lymphoma cells

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Nat Rev Immunol 7:161167 Piletz J, Halaris A, Iqbal O, Hoppensteadt D, Fareed J, Zhu H, Sinacore J, DeVane C (2009) Pro-inflammatory biomakers in depression: treatment with venlafaxine

Often, symptoms like low sex drive, reduced sexual function, weight gain, mood changes, and low energy are dismissed as just part of getting older