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While even extremely high doses of GHK-Cu are unlikely to cause any adverse reactions, Pickart has estimated that the peptide can produce toxic action and start lowering a subjects blood pressure starting from an astronomical dose of about 22,500mg [13]

Weight Fluctuations: Some individuals have reported unintended weight gain or loss, though evidence on this is limited

We conclude that while a consensus in pharmacogenetic management of APAP in pediatric populations has not been achieved, a systems biology based strategy for comprehensively understanding the ontogenic regulatory pathway as well as the interaction between age and genetic variations are particularly necessary in order to address this question

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PMID: 87 mijewskiMA