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In humans, clinical studies have evaluated the effects of NAC treatment on myocardial infarction
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The final covariate models for subject ( i ) and dosing occasion ( j ) were parameterised as follows: where In the above equations, is the estimated (or fixed) value for each covariate, ka.long.fast is the absorption rate constant for fasting times of 120 min or longer, i is the subject-level random effects, j is the occasion-level random effects
It is also not recommended for patients with a history of pancreatitis or thyroid cancer, and individuals with certain allergies
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