Oral BPC: Primarily a Gut Peptide The most biologically plausible use of BPC-157 is the least discussed online: oral administration
Hyperbaric oxygen therapy (HBOT) The use of HBOT in individuals with ASD has been suggested for its ability to increase blood flow in the brain, reduce inflammation, and reduce oxidative stress
Positive effects in IBD and colitis models
Last reviewed: June 8, 2026 Last updated: June 8, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
Avoid mixing strong acids with vitamin C-based lotions, as this can cause irritation
Diagnostic Criteria (Adapted from consensus guidelines): Chronic multisystem symptoms consistent with mast cell activation Evidence of elevated mast cell mediators (during flare or baseline), such as: Serum tryptase Plasma histamine Chromogranin A Urinary N-methylhistamine Urinary prostaglandin D2 or F2 Improvement with medications that block mast cell activity (e.g., antihistamines, cromolyn sodium) Testing is most accurate when done during or soon after a flare , and samples often need to be chilled and analyzed at specialized labs