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Although the gene of this neuropeptide and the exact mechanism of its action remain unknown, it has been found in free and bound form in the hypothalamus, limbic system and pituitary gland

A study by Krivic et al

Welcker, M

Some signs of B12 deficiency: Anemia (megaloblastic) Gastrointestinal lesions Poor nerve health Numbness/tingling sensation Memory loss, disorientation Weakness Personality and mood changes (including depression, dementia) Difficulty waking Some risks for B12 deficiency: Vegetarian, vegan, or low animal product diets Aging Males Caucasian and Latin American descent Malabsorption issues Pregnancy Alcoholism Small bowel resection or stomach surgery What is Vitamin D3

This guide walks through the real differences, where each shines on its own, and why combining them has become the default

Ursini F, Maiorino M, Gregolin C (1985) The selenoenzyme phospholipid hydroperoxide glutathione peroxidase