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Why did semaglutide replace exendin-4 in newer drugs like Ozempic
Metabolic Outcomes Thirty-five of the studies reported changes in HbA1c or body weight
Coprimary endpoints were the percentage change in body weight and weight reduction of 5% or more
In pooled clinical trial data, injection site reactions occurred in 4.6% of tirzepatide-treated patients who developed anti-tirzepatide antibodies, compared to only 0.7% of those who did not develop antibodies
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