Human microsomal prostaglandin E synthase 1: a member of the MAPEG protein superfamily
About 10% of molecular oxygen undergoes ROS-yielding stepwise reduction during such physiological processes as mitochondrial respiration, CYP-mediated processing of endogenous lipophilic compounds, phagocytosis, and synthesis of disulphide (S-S) bonds from cysteine that are needed for proper protein folding in the endoplasmic reticulum (ER) (143)
doi: 10.1097/JW9.0000000000000003
Conjugation of GSH with electrophilic compounds is mainly mediated by the glutathione- S -transferases (GSTs), a super family of Phase II detoxification enzymes
Dopamine, oxidative stress and protein-quinone modifications in parkinsons and other neurodegenerative diseases
Piechota, A., et al., Lipoic acid - biological activity and therapeutic potential