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And shedding pounds may not be the only thing driving cardiovascular gains
Notably, GLP-1 signaling helps regulate higher-order central nervous system functions, including learning and memory, reward processing, and food palatability
Some researchers proposed that UA may act on heart in an early unstable stage of the disease, in the stable stages other factors may overshadow its effects (Maloberti et al., 2021)
10.3390/jpm12040513 J Pers Med
Available online at: 12 CosentinoFGrantPJAboyansVBaileyCJCerielloADelgadoVet al
It also must be considered that SUSTAIN-6 was not designed nor adequately powered to assess DR incidence
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