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Common causes encompass metabolic disorders like fatty acid oxidation defects and organic acidemias, renal issues such as carnitine loss due to chronic renal failure, Fanconi syndrome, dialysis, or certain medications (e.g., vancomycin), dietary factors including vegetarianism, starvation, or specific diets like the ketogenic diet, and liver diseases such as cirrhosis and fatty liver

Q4: How long until results appear

Less ceramide means your skin holds on to moisture less efficiently, and, along with many external factors, your skin barrier becomes damaged

Devlin, S

The good news: fall and winter can be the best time to correct sun damage because youre typically getting less direct sun exposure day to day

And so those plus versions, it's a godsend for them