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Abrupt withdrawal has been linked to severe complications, including Posterior Reversible Encephalopathy Syndrome (PRES), hypertensive encephalopathy, stroke, and death (Thorpe et al., 2025)
A reasonable baseline is around 0.8 grams per kilogram of body weight per day (g/kg/day), or approximately 0.36 grams per pound (g/lb)
Personalized Nutrition & Meal Plans Get nutritious recipes and have GLP-1 friendly meals delivered straight to your door
others transition off successfully
Inflammopharmacology , 30 (3), 1063-1077
Diabetes, Obesity and Metabolism (2026) 3
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