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Given the strong association between MASLD and cardiovascular pathology, that represents the primary cause of death in this population, the cardioprotective benefits of GLP-1 RAs provide important additional clinical value beyond hepatic benefits

Both conditions involve insulin resistance, hormonal imbalance, and difficulty with weight management

People go on and off the medication

If not, getting your metabolism back will take a two-pronged approach

Its currently being tested in large phase 3 clinical trials, expected to run throughout 2026, These studies are designed to confirm how well the drug works, how safe it is, and whether the promising results seen in smaller phase 2 trials can be replicated in larger groups