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Much of the reported 40% lean mass loss with GLP-1 use is coming from the liver, explained exercise physiologist Keith Baar, a professor of Neurobiology, Physiology and Behavior and Physiology and Membrane Biology

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Looking forward, three key research priorities emerge: (1) Mechanistic Elucidation: Future work must precisely define organelle-specific mechanisms, particularly the potential role of lipid droplet-mitochondria cross-talk in airway epithelial cells, and validate these pathways in human COPD samples