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Recent research has found that a persons genetic makeup may explain why some people do not respond to GLP-1 drugs

The Common Threads of Fibromyalgia and Chronic Fatigue Syndrome from Everyday Health, by Dennis Thompson Jr, medically reviewed by Lindsey Marcellin, MD, MPH, reviewed November 23, 2011, viewed on February 27, 2023

It has been suggested that signaling between enteric glia and astrocytes in the brain is implicated in the pathogenesis of some neurodegenerative disorders, such as Alzheimers dementia and Parkinsons disease (PD), that are strongly associated with MDD [33, 34]