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Drug interactions Berberine may inhibit several cytochrome P450 enzymes (including CYP3A4, CYP2D6, and CYP2C9) and P-glycoprotein, potentially affecting the metabolism of numerous medications including statins, anticoagulants, antihypertensives, and immunosuppressants

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Whenever possible, eat these foods raw or minimally heated, since heating and microwaving tend to destroy antioxidants

This is where stress hijacks appetite becomes relevant, because cortisol-driven stress loops can weaken satiety signaling and increase reward-based eating patterns