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According to the American Diabetes Association, GLP-1 therapies are now recommended in many patients with type 2 diabetes and high cardiovascular risk
Rakusa M, et al
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10.1079/pns2006496 4 AshrafN
However, despite advances in delivery systems such as lipid nanoparticles, polymers, viral/bacterial vectors, and exosomes, the efficiency of RNA-based therapeutics to specific organs or cell types is limited [81]
Longuet C, Sinclair EM, Maida A et al (2008) The glucagon receptor is required for the adaptive metabolic response to fasting
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