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The addition of GIP agonism is what separated tirzepatide from pure GLP-1 drugs, and researchers tracking the progression from semaglutide to tirzepatide to retatrutide can see how each additional receptor adds another layer of metabolic benefit

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Reconstitution calculations determine how much water to add for desired concentration

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Reconstitution math for 100mg Standard reconstitution adds 3mL of bacteriostatic water to 100mg, creating a concentration of approximately 33.3mg/mL